Mechanism of Action

Nicotine acts as an agonist at nicotinic acetylcholine receptors (nAChRs) in the central and peripheral nervous systems. When nicotine binds to these receptors, it stimulates the release of neurotransmitters, particularly dopamine, which plays a key role in the brain's reward pathways and contributes to its addictive properties. Additionally, nicotine enhances cognitive function and activates the autonomic nervous system, resulting in increased heart rate and blood pressure. Through these actions, nicotine influences mood, cognition, and various physiological responses.

Indication

 Indicated for the management of nicotine dependence and as an aid in smoking cessation, helping to reduce withdrawal symptoms and cravings associated with quitting smoking.